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FRAIL

Papers on FRAIL

10,415 papers219 new in 30 days

Monday, October 26

ESC Congress 2026 Abstract

Frailty weakens the link between age and heart attack deaths

Compared with patients under 65, those 75 and older had an adjusted odds ratio for in-hospital death of 1.81 if frail against 2.64 if non-frail.Compared with patients under 65, those 75 and older had an adjusted odds ratio for in-hospital death of 1.81 if frail against 2.64 if non-frail.

A heart cross-section with dark damaged tissue stands between smaller hearts with differing damage, upright figures, and scattered dark fragments.
Cohort studyBiomarkers
Paper
Journal of Rehabilitation Medicine

Stroke support had fewer favorable outcomes in patients 80 and older

Among participants aged 80 and older, a favorable outcome occurred in 23.4% of the intervention group compared with 57.0% of controls.Among participants aged 80 and older, a favorable outcome occurred in 23.4% of the intervention group compared with 57.0% of controls.

Overview of the study intervention.
Randomized trial · 66 peopleStroke
Paper
ESC Congress 2026 Abstract

Frailty linked to cardiovascular risks in people with cancer

Over an average 4.5 years, major cardiovascular events occurred in 31.0% of non-frail, 37.3% of pre-frail and 52.5% of frail participants.Over an average 4.5 years, major cardiovascular events occurred in 31.0% of non-frail, 37.3% of pre-frail and 52.5% of frail participants.

A large heart with widened chambers sits beside smaller hearts with more compact chambers and a group of upright, faceless people.
Cohort · 52,285 peopleCancer
Paper
ESC Congress 2026 Abstract

Frailty linked to higher death risk across ages in heart failure

Adjusted hazard ratios comparing death risk over time in frail versus non-frail patients were 2.35 at 70 or younger and 1.78 at 82 or older.Adjusted hazard ratios comparing death risk over time in frail versus non-frail patients were 2.35 at 70 or younger and 1.78 at 82 or older.

A heart cross-section sits among upright groups of people, with more white human-shaped gaps in the gray group than in the blue group.
Cohort · 23,556 peopleHeart failure
Paper
ESC Congress 2026 Abstract

Frailty linked to higher death risk in cardiogenic shock

Hospital death rates with versus without frailty were 39.3% versus 29.8% in older adults and 24.5% versus 16.2% in younger adults.Hospital death rates with versus without frailty were 39.3% versus 29.8% in older adults and 24.5% versus 16.2% in younger adults.

A heart in cross-section towers over small upright blue-green and gray figures, with white figure-shaped gaps scattered among the groups.
Cohort · 207,419 peopleCardiogenic shock
Paper
ESC Congress 2026 Abstract

Illness burden’s link to death is weaker with frailty in heart failure

High versus low illness burden was linked to 42% higher relative death risk in non-frail heart failure patients, versus 13% in frail patients.High versus low illness burden was linked to 42% higher relative death risk in non-frail heart failure patients, versus 13% in frail patients.

A large heart cross-section sits among smaller hearts and upright groups of people, with gray patches on the hearts beside groups containing more dark figures.
Cohort · 18,058 peopleHeart failure
Paper

Sunday, October 25