Advanced Science
Protein in blood vessel cells limited bone loss in animals
In animal experiments, loss of the protein worsened bone degeneration, while restoring it eased osteoporosis caused by removal of the ovaries.In animal experiments, loss of the protein worsened bone degeneration, while restoring it eased osteoporosis caused by removal of the ovaries.
Mouse studyBones and joints
Who was studiedFemale mice with ovariectomy-induced osteoporosis, 5 weeks
What changedBone volume fraction was approximately 2.0-fold higher after endothelial TRX2 restoration in ovariectomized mice than with a control vector
The catchBone preservation was assessed only 5 weeks after injection