Redox Biology·Sep 27Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degenerationExperiments in animalsMechanismsPaper
The Journal of Biological Chemistry·Sep 1Heat shock protein 27 promotes cell cycle progression by down-regulating E2F transcription factor 4 and retinoblastoma family protein p130Experiments in human cellsCell cycle regulationPaper
Stem Cell Research & Therapy·Jun 1miR-10a rejuvenates aged human mesenchymal stem cells and improves heart function after myocardial infarction through KLF4Experiments in miceMesenchymal stem cellsPaper
Biochemical and Biophysical Research Communications·Mar 28Kruppel-like factor 4 regulates keratinocyte senescenceExperiments in cellsCellular senescencePaper
Aging Cell·Mar 7NHR-49/HNF4 integrates regulation of fatty acid metabolism with a protective transcriptional response to oxidative stress and fastingExperiments in wormsOxidative stress and ROS signalingPaper
Nature Communications·Oct 13A conserved KLF-autophagy pathway modulates nematode lifespan and mammalian age-associated vascular dysfunctionExperiments in wormsAutophagyPaper
Archives of Osteoporosis·Jul 14An application of partial least squares for identifying dietary patterns in bone healthCross-sectional study of 2,129 peopleBones and jointsPaper
European Journal of Nutrition·Jun 14A comparison of principal component analysis, partial least-squares and reduced-rank regressions in the identification of dietary patterns associated with bone mass in ageing AustraliansCohort study of 1,182 peopleBones and jointsPaper
Current Opinion in Clinical Nutrition and Metabolic Care·Apr 5Role of ATF4 in skeletal muscle atrophyReviewMusclePaper
PLOS One·Sep 13Gain-of-Function Alleles in Caenorhabditis elegans Nuclear Hormone Receptor nhr-49 Are Functionally DistinctExperiments in wormsMechanismsPaper
Oncotarget·Aug 18Overexpression of KLF4 promotes cell senescence through microRNA-203-survivin-p21 pathwayExperiments in cellsCellular senescencePaper
Neurochemical Research·Jun 4Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged RatsExperiments in ratsTaurinePaper
Neurobiology of Aging·Apr 23Diaminodiphenyl sulfone-induced parkin ameliorates age-dependent dopaminergic neuronal lossExperiments in miceInterventionsPaper
PLOS Genetics·Apr 9Sir2 Acts through Hepatocyte Nuclear Factor 4 to maintain insulin Signaling and Metabolic Homeostasis in DrosophilaExperiments in fliesSirtuin signalingPaper
Journal of the American Heart Association·Mar 18Ideal Cardiovascular Health and Cognitive Aging in the Northern Manhattan StudyCohort study of 1,033 peoplePopulationsPaper
The International Journal of Behavioral Nutrition and Physical Activity·Mar 2A comparison of the dietary patterns derived by principal component analysis and cluster analysis in older AustraliansStudy in peoplePopulationsPaper
Biomaterials·Nov 25Preserved liver-specific functions of hepatocytes in 3D co-culture with endothelial cell sheetsExperiments in rat cellsInterventionsPaper
Journal of Applied Physiology·Aug 20Influence of hormone replacement therapy on eccentric exercise induced myogenic gene expression in postmenopausal womenStudy of 14 peopleHormone replacement therapyPaper
Diabetes Care·Sep 1Insulin resistance syndrome predicts coronary heart disease events in elderly type 2 diabetic menCohort study of 229 peopleCoronary artery diseasePaper