Matrix Biology·Sep 4Hyaluronan and proteoglycan link protein 1 - A novel signaling molecule for rejuvenating aged skinExperiments in animalsSkinPaper
International Journal of Molecular Sciences·Aug 31Citrus Flavanone Effects on the Nrf2-Keap1/GSK3/NF-κB/NLRP3 Regulation and Corticotroph-Stress Hormone Loop in the Old PituitaryExperiments in ratsInterventionsPaper
Antioxidants & Redox Signaling·Aug 13M6A RNA Methylation-Mediated TUG1 Stability Maintains Mitochondrial Homeostasis during Kidney Aging by Epigenetically Regulating PGC1-α ExpressionStudy in peopleEpigenetic regulation of gene expressionPaper
Chemico-biological Interactions·Aug 10Metformin promotes the survival of random skin flaps via the activation of Nrf2/HO-1 signalingExperiments in 24 ratsMetforminPaper
Geriatrics & Gerontology International·Aug 9Nrf2 cell signaling pathway is responsible for the antioxidant effect of resveratrol in agingStudy in peopleResveratrolPaper
American Journal of Physiology Endocrinology and Metabolism·Jul 31The role of interleukin-10 in mitigating endoplasmic reticulum stress in aged mice through exerciseExperiments in miceCombined aerobic and resistance trainingPaper
Experimental Cell Research·Jul 18Mesenchymal stem cells-derived exosomes alleviate senescence of retinal pigment epithelial cells by activating PI3K/AKT-Nrf2 signaling pathway in early diabetic retinopathyExperiments in miceDiabetic retinopathyPaper
Scientific Reports·Jul 8Urolithin A-mediated augmentation of intestinal barrier function through elevated secretory mucin synthesisExperiments in miceUrolithin APaper
Heliyon·Jul 8Nesfatin-1 attenuated lipopolysaccharide-induced inflammatory response and senescence in human dental pulp cellsExperiments in human cellsInterventionsPaper
Translational Research·Jul 1IGF2BP3/NCBP1 complex inhibits renal tubular senescence through regulation of CDK6 mRNA stabilityStudy in peopleCellular senescencePaper
Antioxidants·Jun 27β-Cyclocitral from Lavandula angustifolia Mill. Exerts Anti-Aging Effects on Yeasts and Mammalian Cells via Telomere Protection, Antioxidative Stress, and Autophagy ActivationExperiments in yeastInterventionsPaper
Current Aging Science·Jun 26Aging-associated Aberrant Mitochondrial Redox Signaling, Physical Activity, and SarcopeniaReviewOxidative stress and ROS signalingPaper
International Journal of Ophthalmology·Jun 25SIRT1 inhibits apoptosis of human lens epithelial cells through suppressing endoplasmic reticulum stress in vitro and in vivoExperiments in ratsER unfolded protein responsePaper
Aging and Disease·Jun 25The NRF2/ID2 Axis in Vascular Smooth Muscle Cells: Novel Insights into the Interplay between Vascular Calcification and AgingExperiments in miceNRF2–KEAP1 antioxidant responsePaper
Diabetes·Jun 21Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for β-Cell Function During AgingExperiments in miceMechanismsPaper
Free Radical Biology & Medicine·Jun 19STING1-accelerated vascular smooth muscle cell senescence-associated vascular calcification in diabetes is ameliorated by oleoylethanolamide via improved mitochondrial DNA oxidative damageExperiments in ratsVascular calcificationPaper
Molecular Medicine Reports·May 28gCTRP3 inhibits oophorectomy‑induced osteoporosis by activating the AMPK/SIRT1/Nrf2 signaling pathway in miceExperiments in miceOsteoporosisPaper
Experimental Gerontology·May 28Muscle-specific PGC-1α modulates mitochondrial oxidative stress in aged sarcopenia through regulating Nrf2Experiments in miceNRF2–KEAP1 antioxidant responsePaper
Discovery Medicine·May 27Needle-Free Injection of Metformin Ameliorates Skin Photoaging Through Inhibition of Ferroptosis and Oxidative StressExperiments in ratsMetforminPaper
Advanced Biology·May 22Combined Endurance and Resistance Exercise Mitigates Age-Associated Cardiac DysfunctionExperiments in miceExercisePaper
Chemico-biological Interactions·May 11Mild hyperhomocysteinemia alters oxidative stress profile via Nrf2, inflammation and cholinesterases in cardiovascular system of aged male ratsExperiments in ratsNRF2–KEAP1 antioxidant responsePaper
Current Issues in Molecular Biology·Apr 26Serine Metabolism Regulates the Replicative Senescence of Human Dental Pulp Cells through Histone MethylationExperiments in human cellsMethionine and one-carbon metabolismPaper
Journal of Cachexia, Sarcopenia and Muscle·Apr 20DNA methylation of skeletal muscle function-related secretary factors identifies FGF2 as a potential biomarker for sarcopeniaCase-control study in peopleSarcopeniaPaper
Hua Xi Kou Qiang Yi Xue Za Zhi·Apr 10Effects of surface nanomorphology on the senescence of periodontal ligament stem cellsExperiments in human cellsInterventionsPaper
In Vitro Cellular & Developmental Biology Animal·Mar 28Differences between cultured astrocytes from neonatal and adult Wistar rats: focus on in vitro aging experimental modelsExperiments in rat cellsMechanismsPaper
Molecular Nutrition & Food Research·Mar 24Potential Function of 3,5-Dihydroxy-4-Methoxybenzyl Alcohol from Pacific Oyster (Crassostrea gigas) in Brain of Old MiceExperiments in miceInterventionsPaper
Brain Research·Mar 21Mitochondria-targeting peptide SS-31 attenuates ferroptosis via inhibition of the p38 MAPK signaling pathway in the hippocampus of epileptic ratsExperiments in ratsElamipretidePaper
Journal of Bone and Mineral Research·Mar 13Sarcopenia definitions and their association with fracture risk in older Swedish womenCohort study of 2,883 peopleOsteoporotic fracturesPaper
Nutrition·Mar 2A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated miceExperiments in 10 miceGut and microbiomePaper
Cell Cycle·Feb 23Sirt6 promotes DNA damage repair in osteoarthritis chondrocytes by activating the Keap1/Nrf2/HO-1 signaling pathwayStudy in peopleNRF2–KEAP1 antioxidant responsePaper