ESR2 expression

3 papers study it1 more mentions it2 findings

Humans2
Animals1

Interventions

1

SIRT1-C152

upin mice1

1 study

SIRT1-C152 increases ESR2 expression in mice.
“A single-mutant SIRT1-C152(D) restored the reduced ERβ expression in the endothelium”
AnimalsSIRT1-C152(D)endothelium
SIRT1-mediated ERβ suppression in the endothelium contributes to vascular aging
Aging cellJul 29, 2016

More on SIRT1-C152

Associations

1

Age

downin humans1

1 study

Age is associated with ESR2 expression in humans.
“Significantly higher ERβ H score and percent of expression were associated with the 20-35 years age group”
Humanssun-unprotected and sun-protected skinskinn = 60
Intrinsic versus Extrinsic Aging: A Histopathological, Morphometric and Immunohistochemical Study of Estrogen Receptor β and Androgen Receptor
Skin pharmacology and physiologyJul 12, 2016

Latest

2 papers in 12 months

Frontiers in ImmunologyOct 18

Female hormones enhance skin T cell expansion and suppress IFN-γ production

Study in peopleSkin

Biochemical PharmacologyMar 28

Metformin reduces senescence induced by obesity-related inflammation in luminal breast cancer through estrogen receptor beta modulation

Experiments in human cellsMetformin

Aging CellJul 30

SIRT1-mediated ERβ suppression in the endothelium contributes to vascular aging

Experiments in miceSirtuin signaling

Skin Pharmacology and PhysiologyJul 12

Intrinsic versus Extrinsic Aging: A Histopathological, Morphometric and Immunohistochemical Study of Estrogen Receptor β and Androgen Receptor

Cross-sectional study of 60 peopleSex hormone signaling (estrogen, androgen)