AR expression

1 paper1 finding

In silico1

Associations

1

Age

downin humans1

1 study

Age is associated with AR expression in humans (β = −0.006 log 2 TMM-CPM per year; 4.4% decrease per decade).
“AR expression was negatively associated with age (β = −0.006 log 2 TMM-CPM per year, p < 0.001) corresponding to a 4.4% decrease in expression per decade.”
Reviewhealthy adultsskeletal musclemalesn = 364
MetAR : A semi-automated meta-analysis of skeletal muscle androgen receptors association with age
bioRxiv (Cold Spring Harbor Laboratory)Apr 24, 2026Preprint

Latest

2 in 12 months

Science AdvancesSep 9

Androgen receptor imprints satellite cell stemness and preserves their reservoir for lifelong regeneration and optimal repair

Experiments in miceSex hormone signalling (oestrogen, androgen)

bioRxivApr 24

MetAR : A semi-automated meta-analysis of skeletal muscle androgen receptors association with age

Preprint: computational studySex hormone signalling (oestrogen, androgen)

Cancer ResearchAug 8

Caloric Restriction Enhances the Efficacy of Antiandrogen Therapy in Prostate Cancer by Inhibiting Androgen Receptor Translation

Experiments in miceDietary restriction

Immunity & AgeingMar 25

Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast cancer: a randomized controlled trial

Trial in peopleInterventions

NeuroimmunomodulationSep 22

Age-associated remodeling of neural and nonneural thymic catecholaminergic network affects thymopoietic productivity

ReviewBlood and immune system

The Journal of Biological ChemistryOct 21

Loss of androgen receptor in aging and oxidative stress through Myb protooncoprotein-regulated reciprocal chromatin dynamics of p53 and poly(ADP-ribose) polymerase PARP-1

Experiments in rat cellsEpigenetic regulation of gene expression

Developmental GeneticsJan 1

Age-dependent expression of the androgen receptor gene in the prostate and its implication in glandular differentiation and hyperplasia

Experiments in ratsSex hormone signalling (oestrogen, androgen)