Erythritol
Biomarker2 papers3 findings
- Human trial1
- Humans1
Effects
2Cholesterol in VLDL + LDL containing apoC-III
downin humans1
1 study
Cholesterol in VLDL + LDL containing apoC-III
downin humans1
Erythritol decreases cholesterol in VLDL + LDL containing apoC-III in humans.
Human trialin response to weight-loss dietary interventions2 y
Declines in plasma erythritol and improvements in cardiovascular risk and atherogenic lipid profiles: a 2-year randomized weight-loss dietary intervention trial · The American journal of clinical nutrition · 18 Sep 2026
ASCVD risk score
downin humans1
1 study
ASCVD risk score
downin humans1
Erythritol decreases ASCVD risk score in humans (β: -0.16%; SE: 0.07%).
Human trialper 1 SD reduction, in response to weight-loss dietary interventions6 mon = 664
Declines in plasma erythritol and improvements in cardiovascular risk and atherogenic lipid profiles: a 2-year randomized weight-loss dietary intervention trial · The American journal of clinical nutrition · 18 Sep 2026
Associations
1Ischemic stroke
upin humans1OR 1.246
1 study
Ischemic stroke
upin humans1OR 1.246
Erythritol raises the risk of ischemic stroke in humans (OR 1.246, 95% CI 1.101-1.410).
Humanstwo-sample Mendelian randomization
Risk of Erythritol-Associated Ischemic Stroke: Integrated Genetic, Transcriptomic, and Machine Learning Evidence · International journal of molecular sciences · 31 Aug 2026
Funding
National Institute of Diabetes and Digestive and Kidney DiseasesUS$194.5k1 grant since 2024