ASCVD risk score

Biomarker3 papers3 findings

  • Human trial2
  • Humans1

Interventions

1

Semaglutide

downin humans1−33%Moderate certainty

1 study
  1. Semaglutide decreases ASCVD risk score in humans (-32.6%).

    Human trialin people with HIV with lipohypertrophy32 weeks

    Effects of semaglutide on subclinical cardiovascular health in people with HIV · AIDS (London, England) · 17 Sep 2026

Semaglutide →

Upstream

1

Erythritol

downin humans1

1 study
  1. Erythritol decreases ASCVD risk score in humans (β: -0.16%; SE: 0.07%).

    Human trialper 1 SD reduction, in response to weight-loss dietary interventions6 mon = 664

    Declines in plasma erythritol and improvements in cardiovascular risk and atherogenic lipid profiles: a 2-year randomized weight-loss dietary intervention trial · The American journal of clinical nutrition · 18 Sep 2026

Erythritol →

Associations

1

Cardiovascular disease

upin humans1

1 study
  1. ASCVD risk score predicts cardiovascular disease in humans (AUC 0.927 (95% CI: 0.87-0.98)).

    Humansin people living with HIV in Bogotá, Colombia10 yearsn = 911

    Validation of cardiovascular risk scores in people living with HIV in Colombia · Enfermedades infecciosas y microbiologia clinica (English ed.) · 5 Sep 2026

Cardiovascular disease →

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