Effector CD8+ T cells

There are 4 papers on effector CD8+ T cells in aging research: 2 observational studies in people, 2 in animals. The newest story, Oct 5, 2026: “Nicotinamide riboside improves parasite control in mice”.

Biomarker

4 papers study it25 more mention it1 finding

1 new paper in 30 daysSee all 29 papers on effector CD8+ T cells

  • Humans2
  • Animals2

Interventions

1

ANTI-CD49D antibody

downin mice1

1 study
  1. ANTI-CD49D antibody decreases effector CD8+ T cells in mice (chronic TBI).

    “aCD49d Ab reduces CD8+ T cells exhibiting higher effector status, leading to reduced clonal expansion in aged, but not young, mouse brains with chronic TBI.”

    Animalschronic TBIbrain

    antiCD49d Ab treatment ameliorates age-associated inflammatory response and mitigates CD8+ T-cell cytotoxicity after traumatic brain injury

    bioRxiv : the preprint server for biologyPreprint

More on ANTI-CD49D antibody

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Dec 2025: 1Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 1Oct 2026: 1Nov 2026: 14 papers in 12 months
bioRxiv

Nicotinamide riboside improves parasite control in mice

In mice infected with Trypanosoma cruzi, treatment with the NAD+ precursor improved CD8+ T-cell function and reduced parasite burden in blood and skeletal muscle.In mice infected with Trypanosoma cruzi, treatment with the NAD+ precursor improved CD8+ T-cell function and reduced parasite burden in blood and skeletal muscle.

Preprint: experiments in miceNicotinamide riboside
bioRxiv

T cell KRAS upregulation is linked to premature coronary disease

Profiling blood and plaque samples from 12 patients and 21 controls linked elevated KRAS in senescent CD8+ T cells to premature coronary artery disease.Profiling blood and plaque samples from 12 patients and 21 controls linked elevated KRAS in senescent CD8+ T cells to premature coronary artery disease.

Preprint: case-control study of 21 peopleKRAS

See all 29 papers on effector CD8+ T cells