DNAm-Horvath, PhenoAge, GrimAge and mPoA

1. Cytotoxic chemotherapy has no effect on DNAm-Horvath, PhenoAge, GrimAge and mPoA in humans.

   “increased expression of p16 but not levels of the most common epigenetic clocks (DNAm-Horvath, PhenoAge, GrimAge, mPoA), with the exception of DNAm-Hannum.”

   Humanspatients undergoing cytotoxic chemotherapy treatmentn = 48

   Performance of cellular senescence measure, p16, and DNA methylation clocks in a clinically relevant model of age acceleration

   medRxiv·14 May 2023Preprint

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