DNA/protein ratio

1. Sirtuin signalling is associated with DNA/protein ratio in human cells.

   “Individual targeting of nuclear sirtuins was used to validate impaired DNA/protein ratios experimentally and provided a specific structural footprint associated with sirtuins in the context of cellular senescence.”

   Cellsin cellular senescence

   Biomolecular Fingerprints of Sirtuin Activity in Senescent Fibroblasts Identified via Synchrotron-Based FTIR

   International journal of molecular sciences·29 Oct 2025

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