DNA methylation entropy
4 papers2 findings
- Animals4
Associations
2Gastrulation
downin X. laevis1
1 study
Gastrulation
downin X. laevis1
gastrulation is associated with DNA methylation entropy in X. laevis.
“we found that the epigenetic entropy basepoint maps to the gastrulation stage of embryogenesis”
Animals
bioRxiv (Cold Spring Harbor Laboratory)4 Aug 2022Preprint
Life expectancy
downin mice1
1 study
Life expectancy
downin mice1
DNA methylation entropy predicts life expectancy in mice.
“The progression to disorder, particularly at CpGs that gain methylation over time, was predictive of genotype-dependent life expectancy.”
Animalsat CpGs that gain methylation over time
Genetic loci and metabolic states associated with murine epigenetic aging
eLife7 Apr 2022
Latest
3 in 12 monthsbioRxiv
Heterogeneous epigenetic regulatory patterns link mammalian aging, development, and mortality
Preprint: study in peopleBiomarkers
bioRxiv
Physics-Informed Modeling of Biological Aging through DNA Methylation Entropy
Preprint: computational studyBiomarkers
Molecular Systems Biology
Convergence of aging- and rejuvenation-related epigenetic alterations on PRC2 targets
Experiments in miceEpigenetic regulation of gene expression
bioRxiv
Estimating universal mammalian lifespan via age-associated epigenetic entropy
Preprint: computational studyMechanisms
Genome Biology
DNA methylation entropy as a measure of stem cell replication and aging
Experiments in miceDNA methylation
bioRxiv
Epigenetic profiling and incidence of disrupted development point to gastrulation as aging ground zero in Xenopus laevis
Preprint: experiments in 6,457 frogsBiomarkers
eLife
Genetic loci and metabolic states associated with murine epigenetic aging
Experiments in 339 miceBiomarkers