Papers on diastolic function

356 papers41 new in 30 days

Wednesday, October 9

GeroScienceOct 9

Hyperactive mTORC1/4EBP1 signaling dysregulates proteostasis and accelerates cardiac aging

Experiments in micemTOR signaling

Paper

Tuesday, October 8

bioRxivOct 8

Hyperactive mTORC1/4EBP1 Signaling Dysregulates Proteostasis and Accelerates Cardiac Aging

Preprint: experiments in micemTOR signaling

Paper

Tuesday, September 24

CirculationSep 24

NT-proBNP and Cardiac Troponin I, but Not Cardiac Troponin T, Are Associated With 7-Year Changes in Cardiac Structure and Function in Older Adults: The ARIC Study

Cohort study of 2,006 peopleCardiac troponin I

Paper

Tuesday, August 20

The Journal of PhysiologyAug 20

Plasticity of the heart in response to changes in physical activity

ReviewInterventions

Paper

Friday, August 9

MedicineAug 9

Effects of 6-month administration of tofogliflozin on cardiac function in elderly patients with heart failure with preserved ejection fraction: A retrospective study of a patient cohort

Cohort study in peopleHeart failure with preserved ejection fraction

Paper

Wednesday, July 24

FASEB JournalJul 24

Cardiac diastolic dysfunction by cigarette smoking is associated with mitochondrial integrity in the heart

Study in peopleOxidative phosphorylation

Paper

Monday, July 22

ESC Heart FailureJul 22

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ReviewMechanisms

Paper

Friday, July 12

NMR in BiomedicineJul 12

Hyperpolarized ¹³C and ³¹P MRS detects differences in cardiac energetics, metabolism, and function in obesity, and responses following treatment

Experiments in ratsObesity

Paper

Tuesday, July 9

GeroScienceJul 9

Phosphodiesterase 9A inhibition improves aging-related increase in pulmonary vascular resistance in mice

Experiments in miceLung

Paper

BMC Medical ImagingJul 9

Estimate of the hydraulic force in the aging heart: a cardiovascular magnetic resonance imaging study

Cross-sectional study of 119 peopleBiomarkers

Paper

Monday, July 8

GeroScienceJul 8

Klotho enhances diastolic function in aged hearts through Sirt1-mediated pathways

Experiments in miceInterventions

Paper

Friday, July 5

ESC Heart FailureJul 5

Long-term outcomes of phenoclusters in preclinical heart failure with preserved and mildly reduced ejection fraction

Cohort study of 596 peopleHeart failure

Paper

Monday, June 17

Cardiovascular Drugs and TherapyJun 17

Hydrogen Sulfide Ameliorates Heart Aging by Downregulating Matrix Metalloproteinase-9

Experiments in miceInterventions

Paper

Tuesday, May 14

Journal of the American Society of EchocardiographyMay 14

Association of Cumulative Systolic Blood Pressure With Left Atrial Function in the Setting of Normal Left Atrial Size: The Atherosclerosis Risk in Communities (ARIC) Study

Cohort study of 3,859 peoplePopulations

Paper

Wednesday, May 1

GeroScienceMay 1

Echocardiographic characterization of age- and sex-associated differences in cardiac function and morphometry in nonhuman primates

Study of 38 monkeysMechanisms

Paper

Friday, April 19

American Journal of Physiology Heart and Circulatory PhysiologyApr 19

Phosphorylation of cardiac sodium channel at Ser571 anticipates manifestations of the aging myopathy

Experiments in miceMechanisms

Paper

Monday, April 15

Heart Failure ReviewsApr 15

Resistance is not futile: a systematic review of the benefits, mechanisms and safety of resistance training in people with heart failure

Systematic review of randomized trialsResistance training

Paper

Thursday, April 4

Scientific ReportsApr 4

Aerobic exercise attenuates dysautonomia, cardiac diastolic dysfunctions, and hemodynamic overload in female mice with atherosclerosis

Experiments in 18 miceAerobic exercise

Paper

Friday, March 8

European Journal of Preventive CardiologyMar 8

Wild-type transthyretin cardiac amyloidosis is not rare in elderly subjects: the CATCH screening study

Cross-sectional study of 870 peopleCardiac amyloidosis

Paper

Tuesday, March 5

Circulation Cardiovascular ImagingMar 5

Left Atrial Strain Predicts Subclinical Atrial Fibrillation Detected by Long-term Continuous Monitoring in Elderly High-Risk Individuals

Cohort study of 956 peopleBiomarkers

Paper

Wednesday, January 24

Circulation ResearchJan 24

Indole-3-Propionic Acid Protects Against Heart Failure With Preserved Ejection Fraction

Experiments in miceHeart failure with preserved ejection fraction

Paper

Thursday, November 30

Journal of the American College of CardiologyNov 30

Changes in Pulmonary Artery Pressure Late in Life: The Atherosclerosis Risk in Communities (ARIC) Study

Cohort study of 1,420 peopleLung

Paper

Wednesday, November 15

Diabetes Research and Clinical PracticeNov 15

ACMSD mediated de novo NAD⁺ biosynthetic impairment in cardiac endothelial cells as a potential therapeutic target for diabetic cardiomyopathy

Study in peopleDiabetic cardiomyopathy

Paper

Thursday, November 9

The Journals of Gerontology, Series ANov 9

Sex-Specific Limitation of Cardiac Capacity During the Adult Life Span: Return to Fundamental Structure and Function

Study in peopleMechanisms

Paper

Tuesday, October 31

International Journal of Molecular SciencesOct 31

Age-Related Shift in Cardiac and Metabolic Phenotyping Linked to Inflammatory Cytokines and Antioxidant Status in Mice

Experiments in miceInflammation

Paper

Wednesday, October 25

Nitric OxideOct 25

Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis

Experiments in animalsEndothelial dysfunction

Paper

Thursday, October 19

Journal of Applied PhysiologyOct 19

Effects of aging and endurance exercise training on cardiorespiratory fitness and cardiac structure and function in healthy midlife and older women

ReviewInterventions

Paper

Monday, October 16

Naunyn-Schmiedeberg's Archives of PharmacologyOct 16

Protective effects of Gαi3 deficiency in a murine heart-failure model of β₁-adrenoceptor overexpression

Experiments in miceMechanisms

Paper

Wednesday, October 11

Aging CellOct 11

The role of cardiac resident macrophage in cardiac aging

ReviewMechanisms

Paper

Sunday, October 8

Molecular & Cellular ProteomicsOct 8

Proteomics and β-hydroxybutyrylation Modification Characterization in the Hearts of Naturally Senescent Mice

Experiments in miceMechanisms

Paper