There is 1 paper on delayed rectifier potassium current in aging research: none in people yet, 1 in cells.
1 paper studies it5 more mention it1 finding
See all 6 papers on delayed rectifier potassium current
- Cells1
Upstream
1Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Cellular senescence decreases delayed rectifier potassium current in human cells (Dox-induced senescent-like iCMs compared with untreated iCMs).
“These effects were largely ascribable to augmented late sodium current (INaL) and reduced delayed rectifier potassium current (Ikr).”
CellsDox-induced senescent-like iCMs compared with untreated iCMs0.2 μM doxorubicin3 hours
Theranostics
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2 papers in 12 monthsTheranostics
Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging
Experiments in human cellsCellular senescence
Comparative Biochemistry and Physiology Part A, Molecular & Integrative Physiology
Aging-associated remodeling of ionic currents in ventricular myocytes of seasonal fish Nothobranchius furzeri
Experiments in animalsMechanisms
Bulletin of Experimental Biology and Medicine
Changes in Repolarizing Currents in Mouse Cardiomyocytes Following Chronic Atorvastatin Exposure
Experiments in miceAtorvastatin
The Journal of Physiology
The apicobasal dispersion of ventricular repolarization in humans is associated with age and affects arrhythmia vulnerability
Cross-sectional study of 22 peopleMechanisms