DAF-16 nuclear accumulation

2 papers1 finding

Model organisms2

Upstream

1

daf-2

downin worms1

1 study

daf-2 inhibits DAF-16 nuclear accumulation in worms.
“Here, we show that the DAF-2 pathway prevents DAF-16 accumulation in nuclei.”
Model organismsDAF-2 pathway signalling
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
Nature genetics1 Jun 2001

Latest

2 in 12 months

Brazilian Journal of Medical and Biological Research12 Aug

The flavonoid isoliquiritigenin promotes lifespan extension of Caenorhabditis elegans through the transcription factor DAF-16 and aquaporin-2

Experiments in wormsInterventions

Nature Communications10 Nov

DAF-16/FOXO and HLH-30/TFEB comprise a cooperative regulatory axis controlling tubular lysosome induction in C. elegans

Experiments in wormsFOXO signalling

Experimental Gerontology29 Oct

Cholesterol regulates DAF-16 nuclear localization and fasting-induced longevity in C. elegans

Experiments in wormsMechanisms

Nature Genetics1 Jun

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

Experiments in wormsFOXO signalling