Cytochrome P-450s
6 papers1 finding
- Animals5
- Cells1
Interventions
1Phenobarbital
upin rats1+35%
1 study
Phenobarbital
upin rats1+35%
Phenobarbital increases cytochrome P-450s in rats (+34.5%).
“The cytochrome P-450 content increased by 34.5% in phenobarbital treated female rats in the age of 12 months in comparison with control animals.”
Animalsfemale ratsliver3.5 mg/100 g body weight per dayduring 1-3 days after birthfemales
Effect of enzyme imprinting of liver microsomal monooxygenases upon lifespan of rats
Mechanisms of ageing and development1 Jun 1999
Latest
American Journal of Physiology Endocrinology and Metabolism
Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan
Experiments in miceInterventions
Mechanisms of Ageing and Development
Effect of enzyme imprinting of liver microsomal monooxygenases upon lifespan of rats
Experiments in ratsInterventions
Zhurnal Obshchei Biologii
The microsomal oxidation system of the liver in the aging of animals with various specific lifespans
Experiments in ratsMechanisms
Mechanisms of Ageing and Development
Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice
Experiments in miceBlood and immune system
Archives of Gerontology and Geriatrics
Studies on age related changes in cytochrome P-450, cytochrome b-5 and mixed function oxidase activity in mouse liver microsomes, in relation to their phospholipid composition
Experiments in miceMechanisms
Journal of Gerontology
Inverse correlation between species life span and specific cytochrome P-448 content of cultured fibroblasts
Experiments in cellsMechanisms