Cystathionine

There are 8 papers on cystathionine in aging research: 2 trials and 4 observational studies in people, 2 in animals. The newest story, Oct 26, 2026: “Sulfide supplements prevented heart enlargement in aging mice”.

Biomarker

8 papers study it82 more mention it2 findings

MeSH

1 new paper in 30 daysSee all 90 papers on cystathionine

  • Human trial2
  • Humans4
  • Animals2

Interventions

1

Flaxseed

upin chickens1

1 study
  1. Flaxseed increases cystathionine in chickens (at least 15-fold).

    “dietary flaxseed (via the activity of a vitamin B6 antagonist known as "1-amino d-proline") induced at least 15-fold elevated plasma cystathionine.”

    Animalsdietaryplasmafemales

    Flaxseed Increases Animal Lifespan and Reduces Ovarian Cancer Severity by Toxically Augmenting One-Carbon Metabolism

    Molecules (Basel, Switzerland)

More on Flaxseed

Upstream

1

Older-adults

downin humans1

1 study
  1. Older-adults decrease cystathionine in humans (postprandial response to combined meal and supplement) (p = 0.003).

    “Except for a faster decline of cystathionine in older adults (p = 0.003), the postprandial response of other 1C metabolites was similar between young and older adults.”

    Human trialpostprandial response to combined meal and supplement4 h

    The acute postprandial response of homocysteine to multivitamin and mineral supplementation with a standard meal is not impaired in older compared to younger adults

    European journal of nutrition

Latest

Dec 2025: 3Jan 2026: 2Feb 2026: 0Mar 2026: 2Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 0Sep 2026: 1Oct 2026: 1Nov 2026: 010 papers in 12 months
ESC Congress 2026 Abstract

Sulfide supplements prevented heart enlargement in aging mice

In a mouse experiment, dietary supplementation begun at 9 months restored metabolic balance in the heart and prevented decline across the body.In a mouse experiment, dietary supplementation begun at 9 months restored metabolic balance in the heart and prevented decline across the body.

Mouse studyMechanisms

See all 90 papers on cystathionine