CXCL12 expression

2 papers1 finding

Animals1
Cells1

Interventions

1

Fisetin

downin mice1

1 study

Fisetin decreases CXCL12 expression in mice.
“Senescent ECs exhibited elevated expression of SASP factors, particularly Cxcl12, which was reversed by fisetin supplementation”
Animalssenescent endothelial cellsaortic endothelial cell100 mg/kg/day administered intermittentlyfemale and males
Senolytic Treatment With Fisetin Reverses Age-Related Endothelial Dysfunction Partially Mediated by SASP Factor CXCL12
Aging cell23 Apr 2026

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