Cuproptosis- and ferroptosis-related gene expression

1. Melatonin is associated with cuproptosis- and ferroptosis-related gene expression in humans.

   “gene expression analysis revealed that melatonin modulated cuproptosis and ferroptosis-related genes, including ATP7B and GPX4”

   HumansUndergoing IVF-frozen embryo transfer cycles; more pronounced effects at ≥ 38 yearscumulus cell2 mg daily≥ 8 weeksfemales

   Melatonin supplementation attenuates cuproptosis and ferroptosis in aging cumulus and granulosa cells: potential for improving IVF outcomes in advanced maternal age

   Reproductive biology and endocrinology : RB&E·8 Nov 2024

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