Corrected QT interval

1. Anticholinergic burden was not clearly linked with corrected QT interval in humans (high anticholinergic burden (ACB ≥ 2) vs controls (ACB = 0)).

   “There was no significant difference in terms of heart rate and cQT.”

   Humanshigh anticholinergic burden (ACB ≥ 2) vs controls (ACB = 0)heart

   Effect of anticholinergic burden on cardiac functions in older patients

   Zeitschrift fur Gerontologie und Geriatrie·Jul 1, 2026

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1. Bariatric surgery decreases corrected QT interval in humans (P < 0.003).

   “postoperative assessment revealed a considerable decrease in the heart rate (P < 0.0001) and the corrected QT interval (P < 0.003).”

   Human trialat least six monthsn = 55

   Evaluation of electrocardiographic alterations before and after bariatric surgery

   Global cardiology science & practice·May 15, 2025

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1. Endurance exercise + blood flow restriction decreases corrected QT interval in rats (P<0.01 vs CTL and Sh groups).

   “Exercise plus BFR significantly decreased the corrected QT (QTc) interval (P<0.01 vs CTL and Sh groups)”

   Animalsmales

   Mild exercise along with limb blood-flow restriction modulates the electrocardiogram, angiotensin, and apelin receptors of the heart in aging rats

   Iranian journal of basic medical sciences·Jun 1, 2018

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1. Dimethyldioctylammonium bromide is associated with corrected QT interval in humans.

   “C8-DDAC was related to increased QT interval, QTc interval, and RV5/SV1 amplitude, as well as a reduced QRS time”

   Humansheartfive-monthn = 76

   Quaternary Ammonium Compound Induced Electrocardiogram Abnormalities with Body Fat as a Potential Effect Modifier: A Longitudinal Multiomics Panel Study in Elderly Adults

   Environmental science & technology·Apr 7, 2026

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1. Corrected QT interval is associated with survival in nondiabetic and male patients undergoing dialysis.

   “QTc prolongation was associated with survival in males and nondiabetic patients.”

   Humansin nondiabetic and male patients undergoing dialysis

   Bioelectrical Impedance Phase Angle Value and Prolongations of PR and Corrected QT Intervals in Patients Undergoing Dialysis

   Cardiorenal medicine·Mar 20, 2024

1. Bioelectrical impedance phase angle is associated with corrected QT interval in male and nondiabetic patients undergoing dialysis.

   “An inverse relationship between phase angle value and QTc was observed only in males and nondiabetic patients.”

   Humansin male and nondiabetic patients undergoing dialysis

   Bioelectrical Impedance Phase Angle Value and Prolongations of PR and Corrected QT Intervals in Patients Undergoing Dialysis

   Cardiorenal medicine·Mar 20, 2024

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1. Corrected QT interval is linked with a higher risk of major adverse cardiovascular events in humans (symptomatic atherosclerotic LEAD undergoing endovascular therapy) (HR 1.59, P < 0.001).

   “Multivariate analysis showed that a 1-SD increase in the QTc interval increased the risk of all-cause mortality [hazard ratio (HR) 1.49, P < 0.001] and MACEs (HR 1.59, P < 0.001)”

   Humanssymptomatic atherosclerotic LEAD undergoing endovascular therapymedian 3.15 yearsn = 504

   Association between corrected QT interval and long-term cardiovascular outcomes in elderly patients who had undergone endovascular therapy for lower extremity arterial disease

   Frontiers in cardiovascular medicine·May 12, 2023

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1. Corrected QT interval is linked with a higher risk of mortality in humans (symptomatic atherosclerotic LEAD undergoing endovascular therapy) (HR 1.49, P < 0.001).

   “Multivariate analysis showed that a 1-SD increase in the QTc interval increased the risk of all-cause mortality [hazard ratio (HR) 1.49, P < 0.001]”

   Humanssymptomatic atherosclerotic LEAD undergoing endovascular therapymedian 3.15 yearsn = 504

   Association between corrected QT interval and long-term cardiovascular outcomes in elderly patients who had undergone endovascular therapy for lower extremity arterial disease

   Frontiers in cardiovascular medicine·May 12, 2023

1. Age is associated with corrected QT interval in humans (All correction formulae except QTcBZT in women).

   “QTc and its variance increase with age.”

   HumansAll correction formulae except QTcBZT in women

   Detailed analysis of the impact of age on the QT interval

   Journal of geriatric cardiology : JGC·Sep 1, 2016