Frontiers in Neuroscience
Neuroprotective role of sialic-acid-binding immunoglobulin-like lectin-11 in humanized transgenic mice
Experiments in miceMechanisms
Papers on complement component
70 papers5 new in 30 days
Monday, December 23
Thursday, December 19
GeroScience
Plasma extracellular vesicles carry immune system-related peptides that predict human longevity
Cohort study of 48 peopleBiomarkers
Saturday, November 23
Experimental Eye Research
Choroidal macrophages in homeostasis, aging and age-related macular degeneration
ReviewCellular homeostasis
Monday, October 28
bioRxiv
Genetic removal of Nlrp3 protects against sporadic and R345W Efemp1-induced basal laminar deposit formation
Preprint: experiments in miceNLRP3
Friday, September 27
Trends in Immunology
Intracellular C1q - an unexpected player in neuronal proteostasis
CommentaryMechanisms
Sunday, June 23
medRxiv
Menopause Hormone Replacement Therapy and Lifestyle Factors affect Metabolism and Immune System in the Serum Proteome of Aging Individuals
Preprint: cohort study of 1,890 peopleImmune response
Monday, March 11
European Journal of Applied Physiology
Effects of lunges inserted in walking (eccentric walking) on lower limb muscle strength, physical and cognitive function of regular walkers
Non-randomized trial in 11 peopleMuscle
Saturday, January 27
BMC Geriatrics
Complement component C3 is associated with body composition parameters and sarcopenia in community-dwelling older adults: a cross-sectional study in Japan
Cross-sectional study of 269 peopleSarcopenia
Wednesday, November 22
Sunday, October 22
Clinical Nutrition
The inflammatory potential of diet is associated with the risk of age-related eye diseases
Cohort study of 7,436 peopleEye
Wednesday, January 18
Advanced Materials
Bioengineered 3D Skeletal Muscle Model Reveals Complement 4b as a Cell-Autonomous Mechanism of Impaired Regeneration with Aging
Experiments in cellsComplement system
Friday, October 21
Graefe's Archive for Clinical and Experimental Ophthalmology
Polygenic risk score and biochemical/environmental variables predict a low-risk profile of age-related macular degeneration in Sardinia
Cohort study of 814 peopleAge-related macular degeneration
Tuesday, August 30
Proteomics
Proteomic characteristics of plasma and blood cells in natural aging rhesus monkeys
Experiments in monkeysMechanisms
Saturday, August 13
International Journal of Molecular Sciences
The Complement System, Aging, and Aging-Related Diseases
ReviewComplement system
Saturday, March 26
Wednesday, September 29
The American Journal of Clinical Nutrition
A lifestyle intervention with an energy-restricted Mediterranean diet and physical activity enhances HDL function: a substudy of the PREDIMED-Plus randomized controlled trial
Randomized trial in 391 peopleIntensive lifestyle intervention
Sunday, September 5
Scientific Reports
Changes in plasma C1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention
Non-randomized trial in 15 peopleInterventions
Tuesday, August 24
Brain, Behavior, and Immunity
Dietary DHA prevents cognitive impairment and inflammatory gene expression in aged male rats fed a diet enriched with refined carbohydrates
Experiments in ratsCognitive impairment
Thursday, August 12
Scientific Reports
Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans
Cross-sectional study in peopleComplement system
Saturday, August 7
Brain
The BS variant of C4 protects against age-related loss of white matter microstructural integrity
Genetic association study of 31,128 peopleMechanisms
Wednesday, June 23
eLife
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells
Experiments in miceBones and joints
Thursday, April 1
Research Square
Complement Factor H-Related 3 induces inflammation and complosome activation in human RPE cells
Preprint: experiments in human cellsComplement system
Saturday, September 26
Sunday, August 9
Friday, January 17
Biomarkers in Neuropsychiatry
Complement component 3 levels in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder
Study in peopleMechanisms
Wednesday, July 10
Sunday, February 10
Journal of Clinical Medicine
Effects of Caloric Restriction with Protein Supplementation on Plasma Protein Profiles in Middle-Aged Women with Metabolic Syndrome-A Preliminary Open Study
Non-randomized trial in 7 peopleDietary restriction
Saturday, December 15
Thursday, December 6
Frontiers in Immunology
Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population
Cross-sectional study of 120 peopleComplement system
Tuesday, November 6
Molecular Metabolism
Moderate weight loss attenuates chronic endoplasmic reticulum stress and mitochondrial dysfunction in human obesity
Non-randomized trial in 64 peopleObesity