Intensive lifestyle intervention

Intervention2 papers1 finding

C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.

1 lab in 1 country
  • Human trial2

Outcomes

1

IL-6

downin humans1

1 study
  1. Intensive lifestyle intervention decreases IL-6 in humans (-28.7% vs -11.8%).

    Human trialcompared with diabetes support and education in T2D and overweight/obesitytargeting weight loss1-year

    Residual Inflammatory Risk of Heart Failure and Atherosclerotic CVD in Diabetes: Look AHEAD Ancillary Study · JACC. Heart failure · 2 Sep 2026

IL-6 →

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