Cognitive age
Biomarker1 paper1 finding
- Humans1
Upstream
1Pain severity
upin humans1
1 study
Pain severity
upin humans1
Pain severity increases cognitive age in humans.
Humanshigher pain severity (4+ pain sites)
Chronic pain is linked to an advanced cognitive age pattern · Pain · 24 Sep 2026
Latest
27Probable REM sleep disorder links to Lewy body dementia
In a memory clinic cohort, probable REM sleep behaviour disorder was linked to incident Lewy body dementia with a hazard ratio of 4.82.In a memory clinic cohort, probable REM sleep behaviour disorder was linked to incident Lewy body dementia with a hazard ratio of 4.82.
Cognitive decline after retirement is fastest in rural areas
Post-retirement cognitive decline reached -0.194 points per year in rural areas compared to -0.164 points per year in urban settings.Post-retirement cognitive decline reached -0.194 points per year in rural areas compared to -0.164 points per year in urban settings.
Earlier family loss links to higher cognitive impairment risk
A 20-year longitudinal study finds earlier family bereavement is tied to higher cognitive impairment risk, with child loss remaining robust after…A 20-year longitudinal study finds earlier family bereavement is tied to higher cognitive impairment risk, with child loss remaining robust after health adjustments.
Cognitive test battery validated in older adults in Lebanon
In a study of 3,027 older adults in Lebanon, an adapted cognitive protocol showed good model fit and trajectories aligned with age and education.In a study of 3,027 older adults in Lebanon, an adapted cognitive protocol showed good model fit and trajectories aligned with age and education.
Lifetime alcohol use disorder linked to faster cognitive aging
In a longitudinal cohort, lifetime alcohol use disorder was associated with steeper cognitive decline, equivalent to 7.1 additional years of cognitive…In a longitudinal cohort, lifetime alcohol use disorder was associated with steeper cognitive decline, equivalent to 7.1 additional years of cognitive aging at age 60.
Days exceeding NO2 guidelines linked to faster cognitive decline
Comparing the 75th percentile with the median of NO2 exceedance days, 14-year cognitive decline was -0.09 SD for memory and -0.10 SD for fluency.Comparing the 75th percentile with the median of NO2 exceedance days, 14-year cognitive decline was -0.09 SD for memory and -0.10 SD for fluency.