Clonal hematopoiesis driver mutations
1 paper2 findings
- Humans1
Effects
1Telomere length
no changein humans1
1 study
Telomere length
no changein humans1
Clonal hematopoiesis driver mutations have no effect on telomere length in humans.
“no significant association with age-adjusted telomere length reduction was documented”
Humansn = 2,530
Blood27 Jun 2017
Associations
1X-chromosome inactivation skewing
upin humans1
1 study
X-chromosome inactivation skewing
upin humans1
Clonal hematopoiesis driver mutations are associated with X-chromosome inactivation skewing in humans.
“Mutational burden of both genes correlated with X-inactivation skewing”
Humansn = 2,530
Blood27 Jun 2017
Latest
1 in 12 monthsmedRxiv
Association between DNMT3A-driven clonal hematopoiesis, trained immunity and immune cell function in obesity
Preprint: cohort study in peopleImmune response