Chromosome X loss

1. Chromosome X loss is associated with 45S rDNA copy number in humans.

   “Female X-loss cells additionally exhibited elevated 45S rDNA copy number”

   Humanslymphocytefemales

   Somatic copy-number alteration signatures reveal sex-divergent aging trajectories accelerated in cancer

   bioRxiv (Cold Spring Harbor Laboratory)·23 May 2026Preprint

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