There are 6 papers on cerebrospinal fluid tau in aging research: 1 trial and 4 observational studies in people, 1 review.
6 papers study it11 more mention it4 findings
See all 17 papers on cerebrospinal fluid tau
“showed a negative association between LC-TEC EP and cerebrospinal fluid tau”
- Human trial1
- Humans4
Interventions
1Empagliflozin
downin humans1
1 study
Empagliflozin
downin humans1
Empagliflozin decreases cerebrospinal fluid tau in humans.
“Empagliflozin lowered cerebrospinal fluid tau and modulated CBF”
Human trialoral tablet10 mg q.d.4 weeks
Alzheimer's & dementia : the journal of the Alzheimer's Association
Associations
3Equilibrium probability
downin humans1
1 study
Equilibrium probability
downin humans1
Equilibrium probability is associated with cerebrospinal fluid tau in humans (cognitively normal).
“showed a negative association between LC-TEC EP and cerebrospinal fluid tau”
Humanscognitively normalbrainn = 50
Diffusion MRI tractography of the locus coeruleus-transentorhinal cortex connections using GO-ESP
Magnetic resonance in medicine
Cerebral blood flow
downin humans1
1 study
Cerebral blood flow
downin humans1
Cerebrospinal fluid tau is associated with cerebral blood flow in humans (caudal ACC; APOE ɛ4 carriers; not evident in ɛ4 non-carriers).
“In the cACC, higher CSF tau was associated with higher CTH and lower CBF in ɛ4+, whereas these relationships were not evident in ɛ4-.”
Humanscaudal ACC; APOE ɛ4 carriers; not evident in ɛ4 non-carrierscaudal anterior cingulate cortexn = 45
Journal of Alzheimer's disease : JAD
Cortical thickness
upin humans1
1 study
Cortical thickness
upin humans1
Cerebrospinal fluid tau is associated with cortical thickness in humans (caudal ACC; APOE ɛ4 carriers; not evident in ɛ4 non-carriers).
“In the cACC, higher CSF tau was associated with higher CTH and lower CBF in ɛ4+, whereas these relationships were not evident in ɛ4-.”
Humanscaudal ACC; APOE ɛ4 carriers; not evident in ɛ4 non-carrierscaudal anterior cingulate cortexn = 45
Journal of Alzheimer's disease : JAD