Cdkn1a, Cdkn2a and Il6 expression

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Metformin

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Metformin decreases Cdkn1a, Cdkn2a and Il6 expression in rats.
“Met pre-treatment reversed the upregulation of cdkn1a, cdkn2a, and Il6”
Animalsmetformin pretreatment in cisplatin-treated Sprague-Dawley ratsdorsal root ganglionday 8 post-treatment
Metformin Partially Modulates Cisplatin-Induced Neuronal Senescence but Does Not Prevent Rat Peripheral Sensory Hypersensitivity
Toxicology mechanisms and methods12 Oct 2026

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Metformin Partially Modulates Cisplatin-Induced Neuronal Senescence but Does Not Prevent Rat Peripheral Sensory Hypersensitivity

Experiments in ratsMetformin