Bulk protein synthesis

There are 3 papers on bulk protein synthesis in aging research: none in people yet, 3 in animals. The newest story, Nov 2, 2026: “Fertilization can offset age-related egg changes in mice”.

Biomarker

3 papers study it1 finding

1 new paper in 30 daysSee all 3 papers on bulk protein synthesis

  • Animals2
  • Model organisms1

Interventions

1

Rapamycin

downin mice1

1 study
  1. Rapamycin decreases bulk protein synthesis in mice (8-week treatment; Rap and Rap + Met groups).

    “there were decreases in protein synthesis as assessed by bulk measurements”

    Animals8-week treatment; Rap and Rap + Met groupsliver and skeletal muscle8 weeks

    Sex differences in changes of protein synthesis with rapamycin treatment are minimized when metformin is added to rapamycin

    GeroScience

More on Rapamycin

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 11 paper in 12 months
bioRxiv

Fertilization can offset age-related egg changes in mice

Eggs from aged mice fertilized in the lab formed early embryos at rates comparable to young controls and developed without detectable impairment in young recipients.Eggs from aged mice fertilized in the lab formed early embryos at rates comparable to young controls and developed without detectable impairment in young recipients.

Preprint: mouse studyReproductive system