Bone density

Biomarker

2 papers

Funding

4 grants since 2023

National Institute of Arthritis and Musculoskeletal and Skin DiseasesUS$1.3mNational Institute on AgingUS$1.2mNational Institute of Child Health and Human DevelopmentUS$1.2m

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Medicine

Sex hormone-binding globulin raises lumbar fracture risk

Genetically higher SHBG increased lumbar fracture risk with an odds ratio of 1.201 in FinnGen and 1.005 in UK Biobank, mediated primarily by bone density.Genetically higher SHBG increased lumbar fracture risk with an odds ratio of 1.201 in FinnGen and 1.005 in UK Biobank, mediated primarily by bone density.

Mendelian randomisation in peopleBones and joints