Biological brain aging
1 paper2 findings
- Humans1
Effects
1Cognitive function
mediatesin humans1downin humans1−95% shared variance
1 study
Cognitive function
mediatesin humans1downin humans1−95% shared variance
Biological brain aging mediates cognitive function in humans.
“Furthermore, a mediation analysis revealed that biological brain aging mediated the relationship of vascular risk factors - including hypertension, glucose, obesity, and smoking - to cognitive and motor function.”
Humanseffects of vascular risk factorsn = 40,579
medRxiv : the preprint server for health sciencesJul 24, 2024Preprint
Biological brain aging impairs cognitive function in humans (94.7% of shared variance).
“The PLS identified a latent dimension linking higher markers of biological brain aging to poorer cognitive and motor performances, accounting for 94.7% of shared variance.”
Humansn = 40,579
medRxiv : the preprint server for health sciencesJul 24, 2024Preprint
Latest
13 in 12 monthsExperimental Gerontology
Brain aging clocks: From methodological advances to cellular mechanisms
ReviewBiomarkers
bioRxiv
A cerebrospinal fluid proteomic clock reveals opposing brain-aging programs and predicts neurological disease progression
Preprint: cohort study of 10,000 peopleNeurological disease
Frontiers in Aging Neuroscience
Biological brain aging, cognitive-motor decline and vascular risk: a multivariate imaging analysis of 40,579 individuals
Cohort study of 40,579 peopleBiomarkers
NeuroImage
Advancing brain age estimation: normative deviation mapping (NDM) for sensitive detection of pathological aging
Study of 10,539 peopleBrain age
bioRxiv
BrainYears: A functional EEG-based brain age clock enables intervention-ready measurements of brain aging
Preprint: non-randomized trial in peopleBrain age
IEEE Transactions on Medical Imaging
Temporal Conditioning for Longitudinal Brain MRI Registration and Aging Analysis
Computational studyAI & data
AAIC 2025 Abstract
BrainAge moderates associations between AD biomarkers and cognitive decline: findings from A4/LEARN and the Harvard Aging Brain Study
Cohort study of 1,690 peopleBiomarkers
AAIC 2025 Abstract
BrainAge moderates associations between AD biomarkers and cognitive decline: findings from A4/LEARN and the Harvard Aging Brain Study
Cohort study of 1,690 peopleBiomarkers