Biologic age
Biomarker1 paper1 finding
Associations
1Deep learning
upin humans1
1 study
Deep learning
upin humans1
deep learning predicts biologic age in humans.
Review
Deep Learning Applied to 12-Lead ECGs for Detection of Structural, Metabolic and Systemic Disease · Diagnostics (Basel, Switzerland) · 3 Sep 2026
Funding
National Institute on AgingUS$416.9k1 grant since 2022
Latest
357Blood sugar and fat measures linked to metabolic syndrome risk
In 130,489 Chinese adults with high blood pressure followed for 6–36 months, combined blood sugar and fat measures were more strongly linked to risk…In 130,489 Chinese adults with high blood pressure followed for 6–36 months, combined blood sugar and fat measures were more strongly linked to risk than traditional indicators.
Hormone therapy linked to lower breast cancer mortality
Compared with never-users, hormone therapy ever-users had adjusted hazard ratios, which compare event rates over time, of 0.72 for breast cancer death…Compared with never-users, hormone therapy ever-users had adjusted hazard ratios, which compare event rates over time, of 0.72 for breast cancer death and 1.17 for diagnosis.
Aging index better predicted death in US adults
In 6,896 adults, the index scored 0.893 for predicting death within three years, outperforming three existing age and health measures.In 6,896 adults, the index scored 0.893 for predicting death within three years, outperforming three existing age and health measures.
Biological aging and frailty linked to thinner central retinas
Blood metabolic profiles statistically accounted for 81.14% of the link with one biological age measure, compared with 19.92% for another and 32.27%…Blood metabolic profiles statistically accounted for 81.14% of the link with one biological age measure, compared with 19.92% for another and 32.27% for frailty.
Laboratory methods and quality assurance in the National Longitudinal Study of Adolescent to Adult Health Waves V and VI
Blood protein clock tracks shifts in health risks over time
In an observational study of 4,100 people, accelerated blood protein aging tracked worsening kidney function, blood lipid imbalances, and a higher…In an observational study of 4,100 people, accelerated blood protein aging tracked worsening kidney function, blood lipid imbalances, and a higher risk of death.
Organ aging measures have varied genetic links to disease
An analysis using inherited genetic differences prioritised 31 of 306 assessable comparisons between organ aging measures and age-related conditions…An analysis using inherited genetic differences prioritised 31 of 306 assessable comparisons between organ aging measures and age-related conditions in European-ancestry datasets.
Faster biological aging linked to early colorectal adenocarcinoma
In Korean adults under 50, risk of early-onset colorectal adenocarcinoma was 93% higher in those with accelerated biological aging than in those…In Korean adults under 50, risk of early-onset colorectal adenocarcinoma was 93% higher in those with accelerated biological aging than in those without it.