BioAgeAccel

1. Household income decreases BioAgeAccel in silico (β = -0.41; 95% CI: -0.62, -0.20).

   “household income (β = -0.41; 95% CI: -0.62, -0.20) showed negative associations with BioAgeAccel”

   In silico

   Genetic insights into socioeconomic inequalities and adiposity-related interventions for reducing accelerated biological aging

   International journal of obesity (2005)·10 Feb 2026

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1. Education decreases BioAgeAccel in silico (β = -0.38; 95% CI: -0.48, -0.28).

   “genetically determined education (β = -0.38; 95% confidence interval [CI]: -0.48, -0.28) and household income (β = -0.41; 95% CI: -0.62, -0.20) showed negative associations with BioAgeAccel”

   In silico

   Genetic insights into socioeconomic inequalities and adiposity-related interventions for reducing accelerated biological aging

   International journal of obesity (2005)·10 Feb 2026

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1. Dietary ketogenic ratio increases BioAgeAccel in humans (5.65-year increase).

   “each 1-unit increase in dietary ketogenic ratio (DKR) corresponded to a 5.65-year increase in BioAgeAccel (P < .001)”

   Humansn = 22,026

   Higher dietary ketogenic ratio is associated with accelerated biological aging among US adults: analysis from NHANES 2005-2018

   Nutrition research (New York, N.Y.)·17 Sep 2025

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1. BioAgeAccel has no effect on overall survival in humans.

   “However, the BioAgeAccel was not associated with OS in the chemotherapy cohort.”

   Humansin ICI-naïve patients treated with chemotherapy

   Biological Aging and Survival Outcomes in Patients With Advanced Non-Small Cell Lung Cancer Receiving Systemic Therapy

   Clinical lung cancer·13 Oct 2025

1. Unswitched Memory B Cell decreases BioAgeAccel in humans (β = -0.32, 95% CI: -0.52 to -0.12).

   “Unswitched Memory B Cell showing the strongest protective effect (β = - 0.32, 95% CI:-0.52 to-0.12, p = 1.75 × 10−3)”

   Humans

   Causal effects of immune cell populations on biological aging: a Mendelian randomization study

   Biogerontology·15 Nov 2025

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1. BioAgeAccel raises the risk of stroke in humans (OR 1.35, 95% CI 1.15-1.58).

   “BioAgeAccel: OR 1.35, 95% CI 1.15-1.58”

   Humansn = 37,832

   Association of biological age markers with stroke prevalence: Insights from a cross-sectional study

   Journal of the neurological sciences·26 Feb 2026

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1. BioAgeAccel predicts overall survival in humans.

   “In the ICI cohort, biologically older patients demonstrated significantly worse OS than biologically younger patients, and BioAgeAccel was an independent prognostic factor.”

   Humansin patients treated with immune checkpoint inhibitors

   Biological Aging and Survival Outcomes in Patients With Advanced Non-Small Cell Lung Cancer Receiving Systemic Therapy

   Clinical lung cancer·13 Oct 2025