ATM phosphorylation
1 paper1 finding
- Humans1
Upstream
1MRN complex
upin human cells1
1 study
MRN complex
upin human cells1
MRN complex increases ATM phosphorylation in human cells.
“suppression of MRN attenuated ATM phosphorylation and its downstream signaling molecules”
CellsShown by suppression of MRNCD4 T cell
MRN-ATM Pathway Activation in CD4 T-Cell Senescence during Chronic Hepatitis B Virus Infection
bioRxiv (Cold Spring Harbor Laboratory)18 Mar 2026Preprint
Latest
3 in 12 monthsThe Journal of Clinical Investigation
LSD1-mediated demethylation of the DNA damage response factor ATM promotes senescence and organ aging
Experiments in miceDNA damage response
bioRxiv
MRN-ATM Pathway Activation in CD4 T-Cell Senescence during Chronic Hepatitis B Virus Infection
Preprint: cross-sectional study in peopleCellular senescence
Nature Communications
TRIM37-PARP1-TET1 axis maintains stemness and prevents osteoporosis by inhibiting DNMT1 alternative splicing via 5hmC regulation
Experiments in miceOsteoporosis