Age-related gene expression changes
1 paper2 findings
- Cells1
Interventions
1Somatic cell reprogramming
downin silico1
1 study
Somatic cell reprogramming
downin silico1
Somatic cell reprogramming decreases age-related gene expression changes in silico.
“We found that age-related gene expression changes were reversed during reprogramming, as confirmed by transcriptomic aging clocks.”
In silicocells
Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity
bioRxiv (Cold Spring Harbor Laboratory)Dec 14, 2022Preprint
Somatic cell reprogramming decreases age-related gene expression changes in silico.
“We found that age-related gene expression changes were reversed during reprogramming, as confirmed by transcriptomic aging clocks.”
In silicocells
Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity
bioRxiv (Cold Spring Harbor Laboratory)Dec 14, 2022Preprint
Funding
1 grant since 2021National Institute on AgingUS$370.7k
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