AgingResearch.NewsJoin free

Somatic cell reprogramming

Exposure

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • Funder: National Institute of General Medical Sciences
  • Cells1

Outcomes

1

Age-related gene expression changes

downin silico1

1 study

  1. Somatic cell reprogramming decreases age-related gene expression changes in silico.

    “We found that age-related gene expression changes were reversed during reprogramming, as confirmed by transcriptomic aging clocks.”

    In silicocells

    Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity

    bioRxiv (Cold Spring Harbor Laboratory)Dec 14, 2022Preprint

  2. Somatic cell reprogramming decreases age-related gene expression changes in silico.

    “We found that age-related gene expression changes were reversed during reprogramming, as confirmed by transcriptomic aging clocks.”

    In silicocells

    Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity

    bioRxiv (Cold Spring Harbor Laboratory)Dec 14, 2022Preprint

More on Age-related gene expression changes

Funding

1 grant since 2022

National Institute of General Medical SciencesUS$467.1k

Latest

Related