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Hearing age gap linked to higher mortality in adults

Among 13,331 US adults, each additional year of hearing age gap was associated with higher mortality, with an adjusted hazard ratio of 1.024.

Paper by Xin Qi, Shuo Liu, Qiuchen Zheng, 2 more authorsYu Su · Chinese People's Liberation Army General Hospital
Ear cutaways beside strong and faint sound waves, with white gaps in a dark blue-green group of people and an intact gray group.
Preprint: cohort study of 13,331 US adultsBiomarkers

Dose-response, independent replication

Limit: The mortality association weakened after accounting for average hearing thresholds in the external cohort

Edited by Boris Djordjevic · AgingResearch.News

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In an observational study, researchers analyzed hearing tests and linked death records for 13,331 adults in the US National Health and Nutrition Examination Survey. They trained a machine-learning model to estimate age from 14 measurements of the quietest tones people could hear. The hearing age gap was estimated hearing age minus actual age.

Each additional year of gap was associated with higher mortality after adjustment for other factors. The hazard ratio was 1.024, a measure of the relative rate of death during follow-up. The gap improved risk ranking but not absolute risk prediction. In a separate hospital-based cohort of 2,386 adults in southern China, each additional year was also associated with higher mortality. That association weakened after researchers also accounted for average hearing thresholds.

Why it matters

The study addresses whether age-related hearing patterns carry information about broader health beyond the severity of hearing loss.

Caveats

This observational study in adults cannot show that a larger hearing age gap causes higher mortality. The paper is a preprint and has not yet been peer-reviewed.