International Journal of Cancer

Cancer cases more than quadrupled in Japan’s oldest adults

Cases among people aged 85 or older rose more than four-fold from 1995 to 2020, reaching 15.7% of all cases in 2020.

Graphical abstract from International Journal of Cancer
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Graphical abstract. Tanaka et al.
Cross-sectional study in peoplePopulations
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An observational study used national and prefectural cancer registries to examine cancer in Japanese adults aged 85 or older, comparing them with adults aged 65–84. Researchers analysed new cases, deaths, how far cancers had spread at diagnosis and treatment patterns.

From 1995 to 2020, cancer case numbers in the older group rose by an average of 5.9% a year. Skin and gallbladder or bile duct cancers made up larger shares than in the younger group. Breast and prostate cancers accounted for growing proportions within the older group. Cancers were more often advanced or had no recorded stage at diagnosis. The older group less often received aggressive treatment, even at similar cancer stages.

Why it matters

The authors suggested reconsidering cancer prevention, detection and management to address the needs of an aging population, including guidelines and access to specialists.

Caveats

The observational registry design could not establish what caused the trends or whether treatment differences affected outcomes. The comparison concerned adults aged 85 or older and those aged 65–84 in Japan.