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METTL3/IGF2BP1 Axis Orchestrates m6A-Dependent NCAM1 Preservation to Combat Age-Related Cognitive Decline

By Guohua Ji, Yujie Zhao, Xu Liu, Show 8 more authorsLina Qu
Figure 1. The integrated analysis of transcriptomic and epitranscriptomic data reveals a downregulation of Ncam1 within the hippocampus of SAMP8 mice: (A) Volcano plots of the different expressed m6A-modified…
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Figure 1. The integrated analysis of transcriptomic and epitranscriptomic data reveals a downregulation of Ncam1 within the hippocampus of SAMP8 mice: (A) Volcano plots…The integrated analysis of transcriptomic and epitranscriptomic data reveals a downregulation of Ncam1 within the hippocampus of SAMP8 mice: (A) Volcano plots of the different expressed m6A-modified genes between SAMP8 and SAMR1 mice hippocampus.Ji et al.
Experiments in miceMechanisms

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Guohua Ji, Yujie Zhao, Xu Liu, Show 8 more authorsLina Qu

China Astronaut Research and Training Center

Cells, 15 Sep 2026

doi.org/10.3390/cells15181662PubMed 42782762

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