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Frontiers in Nutrition

Whole wheat bread improves postprandial glucose tolerance in adults with prediabetes: a controlled-feeding randomized crossover trial with microbiome-associated variation in response

By Jillian T. Pierson, Ariana H. Bond, Sisi Cao, Show 11 more authorsRichard S. Bruno
Figure 1. CONSORT diagram illustrating participant flow in a randomized crossover trial evaluating whole wheat and refined white bread consumption on cardiometabolic health in adults with prediabetes.
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Figure 1. CONSORT diagram illustrating participant flow in a randomized crossover trial evaluating whole wheat and refined white bread consumption on cardiometabolic…CONSORT diagram illustrating participant flow in a randomized crossover trial evaluating whole wheat and refined white bread consumption on cardiometabolic health in adults with prediabetes.Pierson et al.
Randomised trial in 39 peopleInterventions

Registered NCT05318183, declared no competing interests

Paper

The paper

Jillian T. Pierson, Ariana H. Bond, Sisi Cao, Show 11 more authorsRichard S. Bruno

The Ohio State University

Frontiers in Nutrition, 28 Aug 2026

doi.org/10.3389/fnut.2026.1907908PubMed 42729417

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