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Multiple molecular pathways to longevity with opposing gene expression programs defining distinct aging strategies in Caenorhabditis elegans

By Zenith D. Rudich, Jiaxi Guan, Aura A Tamez Gonzalez, Show 5 more authorsJeremy M. Van Raamsdonk
Figure 1. Long-lived mutants exhibit significantly extended lifespans of varying magnitudes.
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Figure 1. Long-lived mutants exhibit significantly extended lifespans of varying magnitudes.Long-lived mutants exhibit significantly extended lifespans of varying magnitudes.Rudich et al.
Experiments in wormsMechanisms

Declared no competing interests

Paper

The paper

Zenith D. Rudich, Jiaxi Guan, Aura A Tamez Gonzalez, Show 5 more authorsJeremy M. Van Raamsdonk

Research Institute of the McGill University Health Centre; Van Andel Institute

eLife, 20 Aug 2026

doi.org/10.7554/elife.112139PubMed 42623273

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