Skip to content
AgingResearch.News
  • HomeHome
  • SearchSearch
  • AskAsk
  • FollowingFollowing
  • SavedSaved
AgingResearch.News
bioRxiv

A longevity-associated ubiquitin E3 ligase UBE3C governs lamin B1 homeostasis through selective autophagy and delay senescence

Preprint: experiments in human cellsMechanisms
Paper
  • UBE3C
  • Autophagy
  • LBR
  • LMNB1
  • Cellular senescence
  • Humans

The paper

Guan D, Kim S, Omar K et al.

bioRxiv, 6 Aug 2026, Preprint, not peer-reviewed

doi.org/10.64898/2026.08.05.741138PubMed 42620354

More on Autophagy

  • bioRxiv·9 Oct 2026

    Nuclear anchors weaken in senescent cultured human retinal cells

  • Aging Cell·2 Oct 2026

    Dietary CoQ10 ameliorates megakaryocyte dysfunction in aged mice

  • Nature Aging·6 Oct 2026

    Protein recycling decline hinders senescent cell clearance in mice

  • Advanced Science·9 Oct 2026

    Lamin B1 deficiency impairs bone formation in stem cells

PrivacyTermsContact© 2026 AgingResearch.News

    News

    Trial newsER-100 glaucoma trial findings support testing higher dosesLongevity.Technology and 3 moreResearch newsNew immune cell map reveals how individual immune aging trajectories divergeMedical Xpress and 2 moreResearch newsNewer cohorts of older Europeans show slower intrinsic capacity lossThe Lancet Healthy LongevitySee all news

    Trials

    Phase 2, registered 6 Oct 2026AKG and Brain Health in AgingUniversity of OklahomaRegistered 25 Sept 2026The Effect of Urolithin A (Mitopure®) on Alzheimer's DiseaseUniversity Hospital, AkershusPhase 1, registered 2 Oct 2026Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)Vinmec Research Institute of Stem Cell and Gene TechnologySee all trials

    Trending

    InterventionExercise60 papers, up to trials in peopleGeneAPOE29 papers, up to trials in peopleDiseaseCardiovascular disease113 papers, up to trials in peopleProcessInflammation129 papers, up to trials in peopleBiomarkerBody mass index56 papers, up to trials in peopleInterventionGLP-1 receptor agonists36 papers, up to studies in peopleAll evidence

    Topics

    Mechanisms305Interventions470Biomarkers476Populations604AI & data192Industry & policy21All topics
    • Privacy
    • Terms
    • Contact
    • © 2026 AgingResearch.News