Current Opinion in Rheumatology
Hyper-aging in systemic sclerosis: linking genome instability, mitochondrial dysfunction, and inflammaging to fibrosis
ReviewMechanisms
- Cellular senescence
- cGAS–STING signalling
- DNA damage response
- Systemic sclerosis
- Interstitial lung disease
- Humans
The paper
Department of Genetics; University of Alabama at Birmingham
Current Opinion in Rheumatology, 5 Aug 2026

