Assessment of Factors Influencing Cognitive Status in the Oldest-Old: Evidence From a Community-Based Integrated Healthy Aging Program (YASAM) in Türkiye
Abstract
BackgroundCognitive impairment is a major concern in adults aged ≥80, yet evidence on combined social, clinical, nutritional, and psychological influences remains limited in low- and middle-income settings.ObjectiveTo identify factors associated with cognitive status in community-dwelling oldest-old adults in Türkiye.MethodsThis retrospective cross-sectional study included 295 adults aged ≥80 participating in the YASAM program. Cognitive status, frailty, depression, nutrition, functional ability, and laboratory parameters were assessed using validated tools. Multivariable logistic regression was used to identify factors independently associated with cognitive impairment.ResultsCognitive impairment was present in 34.2% of participants (mean age 84.5 years; 62.7% female). Older age, female sex, lower education, and being unmarried were associated with impairment. Diabetes, chronic kidney disease, and cerebrovascular disease were more common. Higher frailty and depressive symptoms were associated with cognitive impairment, whereas educational attainment, being married, higher nutritional scores, and hemoglobin levels were associated with better cognitive status.
- Cognitive impairment
- Cerebrovascular disease
- Chronic kidney disease
- Depression
- Depressive symptoms
- Humans
The paper
Sağlık Bilimleri Üniversitesi; Selçuk University
Journal of Applied Gerontology, 23 Jun 2026

