Quercetin-Resveratrol Combination Therapy for Elastin Fiber Restoration

Dual targeting of lysyl oxidase (LOX) upregulation and matrix metalloproteinase (MMP-2, MMP-9) inhibition to restore elastin crosslinking and prevent degradation. Quercetin activates SIRT1-mediated LOX expression while resveratrol inhibits NF-κB-driven MMP transcription.