Cognitive training software appears feasible in older adults
In a 12-week randomized feasibility study of 60 older adults with mild cognitive impairment, retention was 95.0% and software-group attendance was 91.3%.
Paper by Cristina Perdomo-Delgado, Rafael Pizarro-Mena, Sonia Rotarou et al.

Limit: Only 60 older adults participated in this feasibility trial
Edited by Boris Djordjevic · AgingResearch.News
A randomized pilot feasibility trial enrolled 60 older adults with mild cognitive impairment, a condition involving difficulties with memory and thinking. Researchers assigned 30 participants to Graffos cognitive training software and 30 to conventional cognitive and functional stimulation. The software program involved two 40-minute sessions weekly for 12 weeks.
Graffos appeared feasible, usable and acceptable. Its group showed greater improvements on a brief test of memory and thinking and on measures of everyday activity performance and satisfaction. The study found no statistically significant differences between groups on two measures of independence in daily activities. Participants described engagement, enjoyment and perceived cognitive benefits. They also identified technical difficulties and a need for more varied activities and adjustable task difficulty.
Why it matters
Mild cognitive impairment may affect independence and quality of life. Testing whether cognitive stimulation software is practical and acceptable helps inform larger trials of its potential benefits.
Caveats
This small feasibility trial was limited to older adults with mild cognitive impairment, and benefits were preliminary. The abstract did not report the size of score improvements or adverse events.
- Graffos
- Mild cognitive impairment
- Barthel index
- Canadian Occupational Performance Measure
- Lawton and Brody Instrumental Activities of Daily Living Scale
- Humans
The paper
Cristina Perdomo-Delgado, Rafael Pizarro-Mena, Sonia Rotarou et al.
Frontiers in Aging, Oct 30, 2026, CC BY, Accepted, not yet published

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