Preprint

Caloric restriction modulates metabolic and endocrine biomarkers (IGF-1, FGF-21, glucose tolerance) in rodents

Preprint: reviewInterventions
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Abstract

Researka accepted publication: 9071bd4f-9969-4a7f-85ee-ae7c64682a16 Source submission: 2c4ae922-ac52-4810-b46b-53263d82a723 Across 4 independently cited sources, the evidence converges on one bounded claim: caloric restriction modulates metabolic and endocrine biomarkers (IGF-1, FGF-21, glucose tolerance) in rodents. Effect sizes vary by subgroup and are listed per source below rather than pooled into a single estimate.

The paper

Preprint, 1 Jan 2026, Preprint, not peer-reviewed

doi.org/10.17605/osf.io/vz697