Preprint

Epicatechin and the Aging Body: A Convergence of Sarcopenia, Nitric Oxide Decline, Mitochondrial Aging, and SIRT1 Restoration

Preprint: reviewInterventions
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Abstract

A research synthesis and novel multi-pathway intervention hypothesis proposing that sarcopenia and vascular aging represent convergent expressions of a tightly interconnected failure network, and that a carefully designed combination of natural interventions may address this network through seven or more independent mechanisms simultaneously. Figures 1 and 2 are provided as a separate file.

The paper

Preprint, 1 Jan 2026, Open access, CC BY, Preprint, not peer-reviewed

doi.org/10.17605/osf.io/dj68z