DEFINING A NOVEL HOMEOSTAT THAT SENSES THE BARRIERS OF PARENTAL REPRODUCTIVE-SPAN AND SETS PROGENY STRESS CAPACITY

Abstract

The ability to respond to stressors quickly and adequately is a core component to survival, and dysregulation of these resistance pathways can be debilitating. The cytoprotective transcription factor SKN-1 plays a critical role in response to multiple types of stress that can impact Caenorhabditis elegans fitness (e.g.