1 paper3 findings
Photoreceptor replacement therapy
updonor photoreceptor neurite extension1updonor photoreceptor survival1upputative donor-host synapse formation1
Photoreceptor replacement therapy is associated with putative donor-host synapse formation in non-human primate.
“some donor PRs forming putative synapses with host bipolar cells (BCs), including midget BCs.”
Animalstissue scaffold loaded with human embryonic stem-cell-derived photoreceptor precursorsretina20 weeks
Donor light-sensing cells may connect in a non-human primate
Stem cell reports13 Oct 2026
Photoreceptor replacement therapy is associated with donor photoreceptor neurite extension in non-human primate.
“with neurite extension by week 7 and some morphological elongation by week 17.”
Animalstissue scaffold loaded with human embryonic stem-cell-derived photoreceptor precursorsretina7 weeks
Donor light-sensing cells may connect in a non-human primate
Stem cell reports13 Oct 2026
Photoreceptor replacement therapy is associated with donor photoreceptor survival in non-human primate (A substantial fraction survived for 20 weeks).
“A substantial fraction of donor PRs survived for 20-weeks”
Animalstissue scaffold loaded with human embryonic stem-cell-derived photoreceptor precursorsretina20 weeks
Donor light-sensing cells may connect in a non-human primate
Stem cell reports13 Oct 2026
A substantial share of donor cells survived 20 weeks after scaffold delivery to a non-human primate retina, with signs of possible connections to host cells.A substantial share of donor cells survived 20 weeks after scaffold delivery to a non-human primate retina, with signs of possible connections to host cells.