Zoster vaccine

2 papers1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Humans1

Associations

Dementia

downin humans1

1 study

Zoster vaccine lowers the risk of dementia in humans (2.48% vs. 2.89%; aHR 0.77, 95% CI 0.64-0.97).
“prior zoster vaccination was associated with lower dementia risk among patients with HZO (2.48% vs. 2.89%; aHR 0.77, 95% CI 0.64-0.97)”
Humansin patients with HZO3 years
Herpes Zoster Ophthalmicus and 3-Year Dementia Risk: Association and Modification by Prior Zoster Vaccination in a Large US Cohort
Cornea18 Aug 2026